Zeitschrift für Infektionstherapie 5.2023
Aktuelle Epidemiologie und Diagnostik in der Mikrobiologie
STD in Deutschland: Wissensstand vs. Wirklichkeit
(Seite 50)
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7. Jansen K. Syphilis in Deutschland im Jahr 2019 – Neuer Höchststand von Infektionen. Epidem Bull 2020; 49:3-13.
8. Rasokat H. Syphilis 2020 – Die Infektionszahlen steigen stetig. Gyn Geburtshilfe 2020; 25:38-44.
9. Haar K. Sechs Jahre STD-Sentinel-Surveillance in Deutschland – Zahlen und Fakten. Epidem Bull 2010; 3:20-27.
10. Matthiesen S, von Rüden U, Dekker A, Briken P, Cerwenka S, Fedorowicz C, Wiessner C. How good is the knowledge about sexually transmitted infections in Germany?: Results of the
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12. Samkange-Zeeb F, Mikolajczyk RT, Zeeb H. Awareness and knowledge of sexually transmitted diseases among secondary school students in two German cities. J Community Health 2013;
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13. Samkange-Zeeb F, Pöttgen S, Zeeb H. Higher risk perception of HIV than of chlamydia and HPV among secondary school students in two German cities. PLoS One 2013; 8:e61636. PMID:
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Übersicht
Unkomplizierte Harnwegsinfektionen – auch ohne Antibiotika? Diagnostik und (nicht)-antibiotische Therapie in der Primärversorgung (Seite 51)
1. Butler C. C. et al. Incidence, severity, help seeking, and management of uncomplicated urinary tract infection: a population-based survey. Br J Gen Pract 2015; 65(639):e702-7. doi: 10.3399/bjgp15X686965
2. Knottnerus B. J. et al. Women with symptoms of uncomplicated urinary tract infection are often willing to delay antibiotic treatment: a prospective cohort study. BMC Fam Pract. 2013;
14:71. doi: 10.1186/1471-2296-14-71
3. Bleidorn J. et al. Why do – or don´t – patients participate in a clinical trial? A qualitative study in German family medicine. GMS Ger Med Sci 2015; published online: Oct 14 2015;
13:Doc1. doi: 10.3205/000221
4. Interdisziplinare S3 Leitlinie: Epidemiologie, Diagnostik,Therapie, Pravention und Management unkomplizierter, bakterieller, ambulant erworbener Harnwegsinfektionen bei erwachsenen
Patienten. Langversion 1.1-2, 2017AWMF Registernummer: 043/044, http://www.awmf.org/uploads/tx_szleitlinien/043044l_S3_Harnwegsinfektionen.pdf
5. Deutsche Gesellschaft für Allgemeinmedizin und Familienmedizin (DEGAM): Brennen beim Wasserlassen. 2018. https://www.degam.de/files/Inhalte/Leitlinien-Inhalte/Dokumente/DEGAM-S3-Leitlinien/053-001_Brennen%20beim%20Wasserlassen/053-001l_Brennen%20Wasserlassen_Langversion_29-08-18.pdf
6. Knottnerus B.J. et al. Toward a simple diagnostic index for acute uncomplicated urinary tract infections. Ann Fam Med. 2013; 11(5):442-51. doi: 10.1370/afm.1513
7. Klingeberg A. et al. Antibiotic-Resistant E. coli in Uncomplicated Community-Acquired Urinary Tract Infection. Dtsch Arztebl Int. 2018; published online Jul 23;115(29-30):494-500.
doi: 10.3238/arztebl.2018.0494
8. Gágyor I. et al. Ibuprofen versus fosfomycin for uncomplicated urinary tract infection in women: randomised controlled trial. BMJ 2015; 351:h6544.
doi: 10.1136/bmj.h6544
9. Vik I. et al. Ibuprofen versus pivmecillinam for uncomplicated urinary tract infection in women-A double-blind, randomized non-inferiority trial. PloS Med 2018; published online May
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10. Kronenberg A. et al. Symptomatic treatment of uncomplicated lower urinary tract infections in the ambulatory setting: randomised, double blind trial. BMJ 2017; 359:j4784. doi:
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11. Kaußner Y. et al. Reducing antibiotic use in uncomplicated urinary tract infections in adult women: a systematic review and individual participant data meta-analysis. Clin Microbiol
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doi: 10.1016/j.cmi.2022.06.017
12. Gágyor I. et al. Herbal treatment with Uva Ursi extract versus fosfomycin for women with uncomplicated urinary tract infection – a double-blind, randomised, controlled comparative
effectiveness phase 4 trial (REGATTA). Clin Microbiol Infect. 2021; 27(10):1441-1447.
doi: 10.1016/j.cmi.2021.05.032
13. Wagenlehner F.M. et al. Non-Antibiotic Herbal Therapy (BNO 1045) versus Antibiotic Therapy (Fosfomycin Trometamol) for the Treatment of Acute Lower Uncomplicated Urinary Tract
Infections in Women: A Double-Blind, Parallel-Group, Randomized, Multicentre, Non-Inferiority Phase III Trial. Urol Int. 2018; 101(3):327–36.
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14. Cooper T.E. et al. D-mannose for preventing and treating urinary tract infections. Cochrane Database Syst Rev. 2022;8(8):CD013608.
doi: 10.1002/14651858.CD013608.pub2
Neueinführung
Impfstoffe gegen das Respiratorische Synzytial-Virus (RSV) – ein Überblick (Seite 52)
1. Robert Koch Institut (RKI). Respiratorische Synzytial-Virus-Infektionen (RSV) – RKI-Ratgeber; Stand 06.02.2018. https://www.rki.de/DE/Content/Infekt/EpidBull/Merkblaetter/Ratgeber_RSV.html#doc2394298bodyText8 [13.09.2023]
2. Rodriguez-Fernandez, R. et al. Monoclonal antibodies for prevention of respiratory syncytial virus infection. Pediatr Infect Dis J 2021; 40(5S): S35-S39.
doi: 10.1097/INF.0000000000003121
3. Fachinformation Arexvy® (Respiratorischer Synzytial-Virus (RSV)-Impfstoff (rekombinant, adjuvantiert)), GlaxoSmithKline
GmbH & Co. KG, Stand 06/2023.
4. Wagner, R., Hildt, E. Zusammensetzung und Wirkmechanismen von Adjuvanzien in zugelassenen viralen Impfstoffen. Bundesgesundheitsbl 2019; 62:462-471.
doi: 10.1007/s00103-019-02921-1
5. Papi, A. et al. Respiratory syncytial virus prefusion F protein vaccine in older adults. N Engl J Med 2023; 388(7):595-608. doi: 10.1056/NEJMoa2209604
6. GlaxoSmithKline (GSK). GSK shares positive data for AREXVY, its respiratory syncytial virus (RSV) older adult vaccine, indicating protection over two RSV seasons. Press release; published online
Jun 21, 2023. https://us.gsk.com/en-us/media/press-releases/gsk-shares-positive-data-for-arexvy-its-respiratory-syncytial-virus-rsv-older-adult-vaccine-indicating-protection-over-two-rsv-seasons/
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7. European Medicines Agency (EMA). First RSV vaccine to protect infants up to 6 months of age and older adults; published online Jul 21, 2023. https://www.ema.europa.eu/en/news/first-rsv-vaccine-protect-infants-6-months-age-older-adults [13.09.2023]
8. Europäische Kommission. EU genehmigt ersten Impfstoff zum Schutz von Säuglingen vor RSV- Infektionen. Pressemitteilung; published online Aug 25, 2023. https://germany.representation.ec.europa.eu/news/eu-genehmigt-ersten-impfstoff-zum-schutz-von-sauglingen-vor-rsv-infektionen-2023-08-25_de [13.09.2023]
9. Full Prescribing Information. ABRYSVOTM (Respiratory Syncytial Virus Vaccine). Pfizer, 08/2023.
10. Kampmann, B. et al. Bivalent prefusion F vaccine in pregnancy to prevent RSV illness in infants. N Engl J Med 2023; 388(16):1451-1464. doi: 10.1056/NEJMoa2216480
11. U.S. Food & Drug Administration (FDA). FDA Approves First Vaccine for Pregnant Individuals to Prevent RSV in Infants. Press Announcement; published online Aug 21, 2023. https://www.fda.gov/news-events/press-announcements/fda-approves-first-vaccine-pregnant-individuals-prevent-rsv-infants [13.09.2023]
12. Fachinformation Abrysvo® (Respiratorischer Synzytial-Virus
(RSV)-Impfstoff (bivalent, rekombinant)). Pfizer, Stand 08/2023.
13. Walsh, E. E. et al. Efficacy and safety of a bivalent RSV prefusion F vaccine in older adults. N Engl J Med 2023; 388(16):1465-1477. doi: 10.1056/NEJMoa2213836
14. vfa. Die forschenden Pharma-Unternehmen. In Entwicklung: Impfstoffe und anderer Schutz vor RSV. published online Sep 6, 2023. https://www.vfa.de/de/arzneimittel-forschung/impfen/schutz-vor-rsv [13.09.2023]